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Found 511 clinical trials

A Prospective Randomized, Double-Blind Comparison of LY900014 to Humalog with an Open-Label Postprandial LY900014 Treatment Group in Children and Adolescents with Type 1 Diabetes PRONTO-Peds

The study medication for this research study is called LY900014.  It is a type of mealtime insulin.  The main reason for you to take part in this study is not to treat you for your diabetes but to help in answering the following research questions: •Does LY900014 help to lower …

1-18 years
All

Improve Postoperative Recovery by Engaging Patients and FAmily-CaregiveRs to End Delirium iPREPARED.

Behavioral intervention aimed at modifying the patient-caregiver dyad’s approach to surgical recovery to mitigate delirium risk, prevent delirium, and reduce delirium symptoms.

60 years and older
All

Gait Monitoring Study.

The purpose of the study is to learn about the gait characteristics of persons with Alzheimer’s disease and related dementias (ADRD). We also want to understand how we should design and implement a tool to monitor gait. To this end, the "Gait Monitoring Study" (a.k.a., AlzInsole) gathers requirements by interviewing …

18 years and older
All

EFFECTS OF ALCOHOLIC HEPATITIS ON IMMUNOLOGICAL AND VIROLOGICAL PROFILES IN HIV-POSITIVE PATIENTS.

The primary objective of this study is to determine the relationships between alcohol consumption and HIV-related pathogenic processes (microbial translocation, immune activation, inflammation, HIV replication, and hepatitis). Two study groups will be assembled and followed longitudinally to address this objective. Group 1 will include HIV-positive, ART-treated, heavy alcohol drinkers who …

21 years and older
All

Profiling of the Gut Microbiome in Overweight Youth with T1D and Associations with Biomarkers of b-cell Stress and Death.

Aim 1 of the study is to profile the gut microbiome in youths with type 1 diabetes according to their body mass index. The central hypothesis is that the gut microbiome will be altered in obese vs. lean youths with T1D (and when compared to healthy non-diabetic lean and obese …

11-18 years
All

Evaluation of Urine as an Anti-Tumor Agent after Exercise.

The purpose of this study is to evaluate anti-tumor capabilities of urine with and without physical exercise, and examine linkage of anti-tumor capabilities to the concentrations of cholesterol and dopamine in the urine.

18 years and older
All

The effectiveness of Taekwondo activity for health benefits among veterans

The purpose of this study is to investigate the effectiveness of Taekwondo activity for health benefits among veterans.

18 years and older
All

Incontinence and Daily Well-Being among Adults with Spina Bifida Study

The purpose of this study is to understand how often people with spina bifida experience either urinary (leaking bladder) or fecal incontinence (leaking stool) from day to day, and to investigate how incontinence impacts their daily feelings and activities.

18-25 years
All

Immunological Profile Changes In Patients with Advanced Non-Small Cell Lung Cancer Undergoing Treatment with Checkpoint Inhibitor Monotherapy

Researchers would like to study how certain biomarkers (signs in your genes that show how well your body responds to a treatment for a disease or condition) change before, during, and after your standard of care treatment for your non-small cell lung cancer (NSCLC). The purpose of this study is …

18 years and older
All

An Open-Label Randomized Phase II Study of Combining Osimertinib with and without Ramucirumab in TKI-naïve EGFR-mutant Locally Advanced or Metastatic NSCLC

Normal 0 false false false EN-US JA X-NONE A phase II study for locally advanced or metastatic non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) gene mutation, will test osimertinib with or without ramucirumab. Researchers hope to determine whether combining these drugs is better at controlling …

18 years and older
All
Phase 2

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