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Found 511 clinical trials

MRI and MRS sequence development optimization and testing Ä

The purpose of this study is to obtain magnetic resonance imaging (MRI) data from head/neck/brain. Ä

18 years and older
All
Phase N/A

Development and testing of non-FDA approved pulse sequences and imaging coils for brain and spine MRI in patients and volunteers

The purpose of this study is to use an investigative MRI sequence or coil that may provide more information and/or higher resolution of the brain and spine, which can help radiologists detect or interpret diseases of the brain and spine.

18 years and older
All
Phase N/A

Targeting Polyamines using DFMO in Persons with Type 1 Diabetes: A Randomized Double-Masked Placebo-Controlled Phase I/II Study to Evaluate the Safety Tolerability and Initial Pharmacodynamics of Multiple Ascending Doses

The purpose of this study is to determine if different doses of a drug known as DFMO have an effect on reducing the amount of stress that is experienced by the body's beta cells and preserves residual c-peptide.

12-40 years
All
Phase N/A

Identification of Serum and Urine Biomarkers of Type 1 Diabetes

The purpose of this study is to identify biomarkers (small molecules in the blood) that can predict those people at risk of developing Type 1 diabetes.

40 years and younger
All
Phase N/A

Ecological Momentary Assessment of Speech and Social Functioning in Serious Mental Illness

The purpose of this study is to learn more about speech and social functioning in everyday life in individuals with Serious Mental Illness.

18 years and older
All
Phase N/A

A Phase 1/2 Study of Nivolumab in Children Adolescents and Young Adults With Recurrent or Refractory Solid Tumors as a Single Agent and in Combination With Ipilimumab

The purpose of this study is to determine the side effects and best dose of nivolumab when given with or without ipilimumab to see how well they work in treating younger patients with solid tumors or sarcomas that have come back (recurrent) or do not respond to treatment (refractory).

1-30 years
All
Phase N/A

Perioperative Pelvic Floor Muscle Training May Improve Recovery of Continence in Men with Localized Prostate Cancer Undergoing Robot-Assisted Radical Prostatectomy

The purpose of this study is to determine if pelvic floor muscle training with a physical therapist before and after surgery will improve health-related quality of life following robot-assisted radical prostatectomy.

18 years and older
Male
Phase N/A

Experts' Actions Completing Mathematics Problems

The purpose of this study is to examine how experts in the field of mathematics and physics go about solving complex mathematical equations.

18 years and older
All
Phase N/A

Neural bases of alcohol-related decision-making

The purpose of this study is to help us better understand addiction and the risk for developing alcoholism and to help us understand how the brain makes choices about drinking alcohol.

21-45 years
All
Phase N/A

Role of keratinocyte-derived cytokines in epidermal injury and atopic dermatitis

The purpose of this study is to examine a protein from the skin of people with atopic dermatitis and compare with those who do not have this disease.

21 years and older
All
Phase N/A

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