Found 511 clinical trials
A Randomized Phase II Study of Partial Breast Irradiation and Sequential vs. Concurrent Chemotherapy in Women with ER Negative Early Stage Breast Cancer (PBI 3.0)
The purpose of this study is to determine whether giving partial breast irradiation and chemotherapy at the same time has the same side effects and outcomes as giving partial breast irradiation and chemotherapy at different times.
Understanding hair follicle structure & pigmentation genetics: expression/methylation differences found in hair growth location.
The purpose of this study is to research on the genes that cause different hair colors in an individual using the genetic information extracted from the hair samples the study participants provide.
The Relationship of Physical Activity on the Risk of Developing a Running Related Overuse Injury
The purpose of this study is: 1) to determine the relationship between experiencing a future running related overuse injury and the physical activity you get outside of running and 2) to determine the volume of inactivity or rest between running bouts that may be protective against the development of experiencing …
Pre-Operative PARPi and Irradiation (POPI) in Women with an Incomplete Response to Neo Adjuvant Chemotherapy (NAC) for Breast Cancer.
The purpose of this study is to determine the number of participants who can handle the treatment within specific safety parameters, determine the number of participants who can handle safely the maximum tolerated dose (MTD) (within 50-200 mg/BID dose range) when combining Veliparib and radiation, as well as to identify …
Phase 2 Study of Imatinib in Children with Neurofibromatosis and Airway Tumors
The purpose of this study is to look at a subset of plexiform neurofibromas and determine if the airway tumors are more sensitive to imatinib therapy.
Immunomodulatory effects of IL-33 in atopic dermatitis
The purpose of this study is to define the effects of neutralizing a certain protein affecting healthy and diseased skin and blood from patients with atopic dermatitis and to determine if the response to neutralization will differ between different subtypes of atopic dermatitis
Finding the Patient's Voice: Development of Practical Approaches for Adolescent and Family Focused Diabetes Prevention Programs
The purpose of this study is to develop and implement a program that can be used by doctors and community groups to help prevent type 2 diabetes in youth.
Active Music Engagement to Manage Acute Distress and Improve Positive Health Outcomes in Young Children undergoing HSCT and Parents
We are trying to find out if music play activities can be used to help decrease parent and young child distress and improve quality of life during stem cell transplant for cancer. We also want to know if this program can help parents and young children cope better with treatment.
Phase Ib/II Study of Neoadjuvant Pembrolizumab With Gemcitabine-Cisplatin (Cisplatin-Eligible) or Gemcitabine (Cisplatin-Ineligible) in Subjects With T2-4aN0M0 Urothelial Cancer: HCRN GU14-188
This is a pre-surgical study involving subjects with muscle invasive bladder cancer, or urothelial cancer, who are candidates for neoadjuvant therapy.
Pathogenetic Basis of Aortopathy and Aortic Valve Disease
The purpose of this study is to identify genes related to aortopathy and aortic valve disease in order to determine the risk and severity of aortic disease in individuals starting at an early age or stage of disease.
