Insulin Clinical Trials

Targeting Polyamines using DFMO in Persons with Type 1 Diabetes: A Randomized Double-Masked Placebo-Controlled Phase I/II Study to Evaluate the Safety Tolerability and Initial Pharmacodynamics of Multiple Ascending Doses

The purpose of this study is to determine if different doses of a drug known as DFMO have an effect on reducing the amount of stress that is experienced by the body's beta cells and preserves residual c-peptide.

Identification of Serum and Urine Biomarkers of Type 1 Diabetes

The purpose of this study is to identify biomarkers (small molecules in the blood) that can predict those people at risk of developing Type 1 diabetes.

Open-label, single-arm, multiple-dose safety, titration, and pharmacokinetic study of AFREZZA® in pediatric subjects ages 4 to 17 years with type 1 diabetes mellitus

The purpose of this research study is to measure how much of the study drug (Afrezza) gets into your bloodafter a single dose and measure how well it works to control your blood sugar level. We also want to make surethis study drug is safe for children and adolescents between …

A Prospective Randomized, Double-Blind Comparison of LY900014 to Humalog with an Open-Label Postprandial LY900014 Treatment Group in Children and Adolescents with Type 1 Diabetes PRONTO-Peds

The study medication for this research study is called LY900014.  It is a type of mealtime insulin.  The main reason for you to take part in this study is not to treat you for your diabetes but to help in answering the following research questions: •Does LY900014 help to lower …

A phase 3 randomized double-blind placebo- and active-controlled parallel-arm trial to assess the efficacy safety and pharmacokinetics of dasiglucagon relative to placebo and GlucaGen? when administered as a rescue therapy for severe hypoglycemia in children with T1DM treated with insulin

This study will compare medications used to treat low blood sugars (hypoglycemia).

None

None

None

None

None