Pediatric Clinical Trials

A listing of Pediatric medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 79 clinical trials
Personal Exposures to Semi-Volatile Organic Compounds in Children of Alaska Native communities

The purpose of this study is to investigate personal exposure to a group of semi-volatile chemicals in children of Alaska Native communities.

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  • 19 Feb, 2024
  • 1 location
A Phase 2 Study of Reduced Therapy for Newly Diagnosed Average-Risk WNT-Driven Medulloblastoma Patients

This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Assessing microstructural and functional connectivity differences between infants with prenatal opioid exposure and opioid naive infants

The purpose of this study is to find whether MRI of the brain can help in identifying infants who will have withdrawal symptoms after prenatal exposure to opioids.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Title: A Phase 2 multicenter open-label study to assess safety and preliminary activity of eribulin mesylate in pediatric subjects with relapsed/refractory rhabdomyosarcoma (RMS) non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) and Ewing sarcoma (EWS)

The purpose of this study is to assess of activity of eribulin mesylate in pediatric subjects with relapsed/refractory RMS, NRSTS or EWS.

  • 0 views
  • 19 Feb, 2024
  • 1 location
AVATAR anesthesia alternative in pediatric radiotherapy: A Multi-Center Pilot

The purpose of this study is to reduce the use of anesthesia during radiation treatments for children.

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  • 19 Feb, 2024
  • 1 location
A Phase 1 Study of Pevonedistat (MLN4924) a Cullin Ligase Inhibitor in Combination With Temozolomide and Irinotecan in Pediatric Patients With Recurrent or Refractory Solid Tumors

This phase I trial studies the side effects and best dose of pevonedistat when giving together with irinotecan hydrochloride and temozolomide in treating patients with solid tumors or lymphoma that have come back after a period of improvement or that do not respond to treatment.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients With Non-high-Risk Neuroblastoma: A Groupwide Historically Controlled Phase III Study

This phase III trial studies how well response and biology-based risk factor-guided therapy works in treating younger patients with non-high risk neuroblastoma.

  • 0 views
  • 19 Feb, 2024
  • 1 location
A Phase 1 Multi-center Open-label Dose De-escalation Study to Evaluate the Safety and Efficacy of Talimogene Laherparepvec in Pediatric Subjects with Advanced Non-Central Nervous System Tumors That are Amenable to Direct Injection

This is a phase 1 study to evaluate the safety of intralesional talimogene laherparepvec administration in pediatric subjects with advanced non-CNS tumors that are amenable to direct injection.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Prospective Randomized Open Label Multi-center Study of the Safety and Pharmacokinetics of Apixaban versus Vitamin K Antagonist or Low Molecular Weight Heparin in Pediatric Subjects with Congenital or Acquired Heart Disease Requiring Chronic Anticoagulation for Thromboembolism Prevention

The purpose of this study is to find out whether apixaban is safe for children to take, and how much apixaban will be in their blood when they take a certain apixaban dose. We will compare apixaban to other blood thinners commonly used.

  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-Human Phase I Trial to Determine the Safety and the Pharmacokinetic Profile of DSP-0337 in Patients With Advanced Solid Tumors

This is a Phase 1, open label, multi-center study of orally administered DSP-0337 in adult subjects with advance solid tumors that are refractory to standard treatment, or for whom no effective therapy exists.

  • 0 views
  • 19 Feb, 2024
  • 1 location